Management Team

John Randle

PhD, Senior Vice President Research & Development

Dr. John C.R. Randle, PhD, brings over 30 years of practical, hands-on experience to the business of drug candidate selection and development.

Dr. Randle has a strong scientific educational foundation with graduate, post-graduate and pharmaceutical discovery research experience creating product candidates from biomedical concepts.

He is the author of over 50 original and review articles and an inventor on 13 patents & applications. He advanced over 20 compounds/products in development from preclinical through Phase 3 clinical planning, including 7 IND/CTAs and program leadership for telaprevir (VX-950, Incivek®) from Phase 1 through late Phase 2 trials.

Other Team Members

Sylvie Breton

Professor Sylvie Breton, PhD, is a Professor of Medicine at Harvard Medical School, and directs the Breton Laboratory within the Program in Membrane Biology / Center for Systems Biology in the Nephrology Division at the Massachusetts General Hospital.

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Glenn Batchelder

Mr. Glenn Batchelder previously was Co-Founder and CEO of Civitas Therapeutics, a development stage pulmonary delivery therapeutic company based on the ARCUS technology platform that was sold to Acorda Therapeutics.

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Andrea Franz

Ms. Franz is a financial executive with over 25 years of experience in small to mid-size biotechnology companies.

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Dennis Ausiello, MD

Dennis A. Ausiello, MD, is the Director of the Center for Assessment Technology and Continuous Health (CATCH) at MGH; Jackson Distinguished Professor of Clinical Medicine, Emeritus at Harvard Medical School; and the Physician-in-Chief, Emeritus of the Department of Medicine at MGH.

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Dennis Brown, PhD

Prof. Dennis Brown is an internationally recognized expert on renal physiology and kidney function at the Massachusetts General Hospital (Nephrology Division) and Harvard Medical School.

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Martin Freed, MD

Dr. Martin Freed brings more than 25 years of strategic development and operational expertise from across the biopharmaceutical and life sciences industries.

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Todd Rosengart, MD

Dr. Todd Rosengart is a nationally recognized cardiothoracic surgeon, a National Institutes of Health (NIH)-supported scientist, and an extensively published investigator.

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Sushrat Waikar, MD, Mph

Sushrut Waikar, MD, MPH, Clinical Advisor, is Associate Professor of Medicine, BWH/HMS. He is Director of Translational Research and Ambulatory Services, BWH and is an expert in acute and chronic kidney disease.

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Winfred W. Williams, MD

Winfred W. Williams, MD, Medical Advisor, is Nephrologist and Associate Chief of the Division of Nephrology at MGH/HMS. He is Director of the Program in Interventional Nephrology for the Transplantation Unit at MGH.

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