Kidney
Pro-inflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice
Battistone MA, Mendelsohn AC, Spallanzani RG, Allegretti AS, Liberman RN, Sesma J, Kalim S,, Wall SM, Bonventre JV, Lazarowski ER, Brown D, and Breton S
Journal of Clinical Investigation – Online Prepublication
Transcriptomes of major renal collecting-duct cell types in mouse identified by single-cell RNA-Seq
Chen L, Lee JW, Chou C-L, Nair A, Battistone MA, Paunescu TG, Merkulova M, Breton S, Verlander JW, Wall S, Brown D, Burg MB, and Knepper MA
PNAS – November 2017
Lung
Structure-Activity Relationship of Heterocyclic P2Y14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres
Veronica Salmasoo , Zhiwei Wen, John M Bennett, Ngan B Phung, David I Lieberman, Varun Gopinatth, John C R Randle, Zhoumou Chen, Daniela Salvemini , Tadeusz P Karcz, Donald N Cook , Kenneth A Jacobson
J Med Chem – April 2021
Exploration of Alternative Scaffolds for P2Y14 Receptor Antagonists Containing a Biaryl Core.
Jung YH, Yu J, Wen Z, Salmaso V, Karcz TP, Phung NB, Chen Z, Duca S, Bennett JM, Dudas S, Salvemini D, Gao ZG, Cook DN, Jacobson KA.
J Med Chem – September 2020
Female Reproductive Tract
The UDP-Glucose Receptor P2RY14 Triggers Innate Mucosal Immunity in the Female Reproductive Tract by Inducing IL-8
Arase T, Uchida H, Kajitani T, Ono M, Tamaki K, Oda H, Nishikawa S, Kagami M, Nagashima T, Masuda M, Asada H, Yoshimura Y and Maruyama TJournal of Immunol. – June 2009